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Inhibition of the PCR by genomic DNA

AIMS: qPCR, is widely used for quantifying minimal residual disease (MRD) and is conventionally performed according to guidelines proposed by the EuroMRD consortium. However it often fails when quantifying MRD levels below 10(−4). By contrast, HAT-PCR, a recent modification designed to minimise fals...

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Detalles Bibliográficos
Autores principales: Latham, Sue, Hughes, Elizabeth, Budgen, Bradley, Morley, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120932/
https://www.ncbi.nlm.nih.gov/pubmed/37083935
http://dx.doi.org/10.1371/journal.pone.0284538