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Dynamic coupling between conformations and nucleotide states in DNA gyrase

Gyrase is an essential bacterial molecular motor that supercoils DNA using a conformational cycle in which chiral wrapping of >100 basepairs confers directionality on topoisomerization. To understand the mechanism of this nucleoprotein machine, global structural transitions must be mapped onto th...

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Detalles Bibliográficos
Autores principales: Basu, Aakash, Hobson, Matthew, Lebel, Paul, Fernandes, Louis E., Tretter, Elsa M., Berger, James M., Bryant, Zev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121156/
https://www.ncbi.nlm.nih.gov/pubmed/29662209
http://dx.doi.org/10.1038/s41589-018-0037-0

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