Structural basis for CEP192-mediated regulation of centrosomal AURKA

Aurora kinase A (AURKA) performs critical functions in mitosis. Thus, the activity and subcellular localization of AURKA are tightly regulated and depend on diverse factors including interactions with the multiple binding cofactors. How these different cofactors regulate AURKA to elicit different le...

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Detalles Bibliográficos
Autores principales: Park, Jin-Gyeong, Jeon, Hanul, Shin, Sangchul, Song, Chiman, Lee, Hyomin, Kim, Nak-Kyoon, Kim, Eunice EunKyeong, Hwang, Kwang Yeon, Lee, Bong-Jin, Lee, In-Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121170/
https://www.ncbi.nlm.nih.gov/pubmed/37083534
http://dx.doi.org/10.1126/sciadv.adf8582

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