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Taurocholic acid promotes hepatic stellate cell activation via S1PR2/p38 MAPK/YAP signaling under cholestatic conditions
BACKGROUND/AIMS: Disrupted bile acid regulation and accumulation in the liver can contribute to progressive liver damage and fibrosis. However, the effects of bile acids on the activation of hepatic stellate cells (HSCs) remain unclear. This study investigated the effects of bile acids on HSC activa...
Autores principales: | Yang, Jing, Tang, Xujiao, Liang, Zhu, Chen, Mingzhu, Sun, Lixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association for the Study of the Liver
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121313/ https://www.ncbi.nlm.nih.gov/pubmed/36800698 http://dx.doi.org/10.3350/cmh.2022.0327 |
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