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Taurocholic acid promotes hepatic stellate cell activation via S1PR2/p38 MAPK/YAP signaling under cholestatic conditions

BACKGROUND/AIMS: Disrupted bile acid regulation and accumulation in the liver can contribute to progressive liver damage and fibrosis. However, the effects of bile acids on the activation of hepatic stellate cells (HSCs) remain unclear. This study investigated the effects of bile acids on HSC activa...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Tang, Xujiao, Liang, Zhu, Chen, Mingzhu, Sun, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121313/
https://www.ncbi.nlm.nih.gov/pubmed/36800698
http://dx.doi.org/10.3350/cmh.2022.0327

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