CCL2 is required for initiation but not persistence of HIV infection mediated neurocognitive disease in mice

HIV enters the brain within days of infection causing neurocognitive impairment (NCI) in up to half of infected people despite suppressive antiretroviral therapy. The virus is believed to enter the brain in infected monocytes through chemotaxis to the major monocyte chemokine, CCL2, but the roles of...

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Detalles Bibliográficos
Autores principales: Kim, Boe-Hyun, Hadas, Eran, Kelschenbach, Jennifer, Chao, Wei, Gu, Chao-Jiang, Potash, Mary Jane, Volsky, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121554/
https://www.ncbi.nlm.nih.gov/pubmed/37085605
http://dx.doi.org/10.1038/s41598-023-33491-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121554/
https://www.ncbi.nlm.nih.gov/pubmed/37085605
http://dx.doi.org/10.1038/s41598-023-33491-7

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