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Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study

Caesarean section (CS) birth is widely reported to be a risk factor for childhood obesity. Although susceptibility to childhood obesity is influenced by race and ethnicity, it is unclear whether this risk of childhood obesity with CS birth also applies in the Japanese population. We investigated the...

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Autores principales: Terashita, Shintaro, Yoshida, Taketoshi, Matsumura, Kenta, Hatakeyama, Takehiro, Inadera, Hidekuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121560/
https://www.ncbi.nlm.nih.gov/pubmed/37085536
http://dx.doi.org/10.1038/s41598-023-33653-7
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author Terashita, Shintaro
Yoshida, Taketoshi
Matsumura, Kenta
Hatakeyama, Takehiro
Inadera, Hidekuni
author_facet Terashita, Shintaro
Yoshida, Taketoshi
Matsumura, Kenta
Hatakeyama, Takehiro
Inadera, Hidekuni
author_sort Terashita, Shintaro
collection PubMed
description Caesarean section (CS) birth is widely reported to be a risk factor for childhood obesity. Although susceptibility to childhood obesity is influenced by race and ethnicity, it is unclear whether this risk of childhood obesity with CS birth also applies in the Japanese population. We investigated the impact of CS birth on obesity at 3 years of age in Japanese children. We obtained data from 60,769 mother–toddler pairs in the Japan Environment and Children’s Study, a large-scale birth cohort study. Obesity was determined by body mass index measured at 3 years of age. Analysis revealed that 11,241 toddlers (18.5%) had a CS birth and that 4912 toddlers (8.1%) were obese. The adjusted risk ratio for obesity at 3 years of age when born by CS compared with vaginal delivery, estimated using inverse probability of treatment weighting, was 1.16 (95% confidence interval 1.08–1.25). These results suggest that CS birth modestly increases the risk of obesity at 3 years of age in Japanese children.
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spelling pubmed-101215602023-04-23 Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study Terashita, Shintaro Yoshida, Taketoshi Matsumura, Kenta Hatakeyama, Takehiro Inadera, Hidekuni Sci Rep Article Caesarean section (CS) birth is widely reported to be a risk factor for childhood obesity. Although susceptibility to childhood obesity is influenced by race and ethnicity, it is unclear whether this risk of childhood obesity with CS birth also applies in the Japanese population. We investigated the impact of CS birth on obesity at 3 years of age in Japanese children. We obtained data from 60,769 mother–toddler pairs in the Japan Environment and Children’s Study, a large-scale birth cohort study. Obesity was determined by body mass index measured at 3 years of age. Analysis revealed that 11,241 toddlers (18.5%) had a CS birth and that 4912 toddlers (8.1%) were obese. The adjusted risk ratio for obesity at 3 years of age when born by CS compared with vaginal delivery, estimated using inverse probability of treatment weighting, was 1.16 (95% confidence interval 1.08–1.25). These results suggest that CS birth modestly increases the risk of obesity at 3 years of age in Japanese children. Nature Publishing Group UK 2023-04-21 /pmc/articles/PMC10121560/ /pubmed/37085536 http://dx.doi.org/10.1038/s41598-023-33653-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Terashita, Shintaro
Yoshida, Taketoshi
Matsumura, Kenta
Hatakeyama, Takehiro
Inadera, Hidekuni
Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
title Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
title_full Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
title_fullStr Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
title_full_unstemmed Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
title_short Caesarean section and childhood obesity at age 3 years derived from the Japan Environment and Children’s Study
title_sort caesarean section and childhood obesity at age 3 years derived from the japan environment and children’s study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121560/
https://www.ncbi.nlm.nih.gov/pubmed/37085536
http://dx.doi.org/10.1038/s41598-023-33653-7
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