Green tea extract prevents CPT-11-induced diarrhea by regulating the gut microbiota

Irinotecan (CPT-11) is an anticancer drug with indications for use in treating various cancers, but severe diarrhea develops as a side effect. We investigated the effects of green tea extract (GTE) on CPT-11-induced diarrhea, focusing on β-glucuronidase and intestinal UGT1A1. When CPT-11 was adminis...

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Detalles Bibliográficos
Autores principales: Kon, Risako, Ikarashi, Nobutomo, Yamaguchi, Arisa, Teshima, Yuka, Yamaguchi, Tamami, Miyaoka, Kanako, Fukuda, Moeno, Noguchi, Hinata, Tomimoto, Rei, Sakai, Hiroyasu, Kamei, Junzo, Hosoe, Tomoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121581/
https://www.ncbi.nlm.nih.gov/pubmed/37085597
http://dx.doi.org/10.1038/s41598-023-33731-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121581/
https://www.ncbi.nlm.nih.gov/pubmed/37085597
http://dx.doi.org/10.1038/s41598-023-33731-w

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