Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

Highly coordinated changes in gene expression underlie T cell activation and exhaustion. However, the mechanisms by which such programs are regulated and how these may be targeted for therapeutic benefit remain poorly understood. Here, we comprehensively profile the genomic occupancy of mSWI/SNF chr...

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Detalles Bibliográficos
Autores principales: Battistello, Elena, Hixon, Kimberlee A., Comstock, Dawn E., Collings, Clayton K., Chen, Xufeng, Hernaez, Javier Rodriguez, Lee, Soobeom, Cervantes, Kasey S., Hinkley, Madeline M., Ntatsoulis, Konstantinos, Cesarano, Annamaria, Hockemeyer, Kathryn, Haining, W. Nicholas, Witkowski, Matthew T., Qi, Jun, Tsirigos, Aristotelis, Perna, Fabiana, Aifantis, Iannis, Kadoch, Cigall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121856/
https://www.ncbi.nlm.nih.gov/pubmed/36944333
http://dx.doi.org/10.1016/j.molcel.2023.02.026

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