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Fosgonimeton, a Novel Positive Modulator of the HGF/MET System, Promotes Neurotrophic and Procognitive Effects in Models of Dementia

All types of dementia, including Alzheimer’s disease, are debilitating neurodegenerative conditions marked by compromised cognitive function for which there are few effective treatments. Positive modulation of hepatocyte growth factor (HGF)/MET, a critical neurotrophic signaling system, may promote...

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Detalles Bibliográficos
Autores principales: Johnston, Jewel L., Reda, Sherif M., Setti, Sharay E., Taylor, Robert W., Berthiaume, Andrée-Anne, Walker, William E., Wu, Wei, Moebius, Hans J., Church, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121968/
https://www.ncbi.nlm.nih.gov/pubmed/36538176
http://dx.doi.org/10.1007/s13311-022-01325-5