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Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling

Maximizing the potential of human kidney organoids for drug testing and regenerative medicine and to model development and disease requires addressing cell immaturity, the lack of a mature collecting system, and off-target cell types. By independently generating two kidney progenitor cell population...

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Detalles Bibliográficos
Autores principales: Uchimura, Kohei, Wu, Haojia, Yoshimura, Yasuhiro, Humphreys, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122187/
https://www.ncbi.nlm.nih.gov/pubmed/33326782
http://dx.doi.org/10.1016/j.celrep.2020.108514