Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction

Myocardial infarction (MI) accelerates immune ageing characterised by lymphopenia, expansion of terminally differentiated CD8(+) T-lymphocytes (CD8(+) T(EMRA)) and inflammation. Pre-clinical data showed that TA-65, an oral telomerase activator, reduced immune ageing and inflammation after MI. We con...

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Detalles Bibliográficos
Autores principales: Bawamia, Bilal, Spray, Luke, Wangsaputra, Vincent K., Bennaceur, Karim, Vahabi, Sharareh, Stellos, Konstantinos, Kharatikoopaei, Ehsan, Ogundimu, Emmanuel, Gale, Chris P., Keavney, Bernard, Maier, Rebecca, Hancock, Helen, Richardson, Gavin, Austin, David, Spyridopoulos, Ioakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122201/
https://www.ncbi.nlm.nih.gov/pubmed/37086366
http://dx.doi.org/10.1007/s11357-023-00794-6

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