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Intranasal Leukemia Inhibitory Factor Attenuates Gliosis and Axonal Injury and Improves Sensorimotor Function After a Mild Pediatric Traumatic Brain Injury

Leukemia inhibitory factor (LIF) is a neuroprotective cytokine that is essential for appropriate glial responses, remyelination, and preservation of neuronal conductance after injury. The intranasal route for delivery of therapeutics to the central nervous system is of particular interest given that...

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Detalles Bibliográficos
Autores principales: D'Mello, Veera, Subramaniam, Malini, Bhalla, Aditya Paul, Saavedra, Sherlyn, Leiba, Ofri, Levison, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122240/
https://www.ncbi.nlm.nih.gov/pubmed/37095853
http://dx.doi.org/10.1089/neur.2021.0075