Cargando…
Intranasal Leukemia Inhibitory Factor Attenuates Gliosis and Axonal Injury and Improves Sensorimotor Function After a Mild Pediatric Traumatic Brain Injury
Leukemia inhibitory factor (LIF) is a neuroprotective cytokine that is essential for appropriate glial responses, remyelination, and preservation of neuronal conductance after injury. The intranasal route for delivery of therapeutics to the central nervous system is of particular interest given that...
Autores principales: | D'Mello, Veera, Subramaniam, Malini, Bhalla, Aditya Paul, Saavedra, Sherlyn, Leiba, Ofri, Levison, Steven W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122240/ https://www.ncbi.nlm.nih.gov/pubmed/37095853 http://dx.doi.org/10.1089/neur.2021.0075 |
Ejemplares similares
-
Neurodegeneration and Sensorimotor Deficits in the Mouse Model of Traumatic Brain Injury
por: Bhowmick, Saurav, et al.
Publicado: (2018) -
Intercellular Adhesion Molecule-1-Induced Posttraumatic Brain Injury Neuropathology in the Prefrontal Cortex and Hippocampus Leads to Sensorimotor Function Deficits and Psychological Stress
por: Bhowmick, Saurav, et al.
Publicado: (2021) -
Proneurotrophins Induce Apoptotic Neuronal Death After
Controlled Cortical Impact Injury in Adult Mice
por: Montroull, Laura E., et al.
Publicado: (2020) -
Immunocal(®) limits gliosis in mouse models of repetitive mild-moderate traumatic brain injury
por: Koza, Lilia A., et al.
Publicado: (2023) -
Inhibitory effects of minocycline on gliosis in the hydrocephalic H-Tx rat
por: Miller, Janet M, et al.
Publicado: (2006)