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Senescent epithelial cells remodel the microenvironment for the progression of oral submucous fibrosis through secreting TGF-β1

OBJECTIVES: Cellular senescence is strongly associated with fibrosis and tumorigenesis. However, whether the epithelium of oral submucous fibrosis (OSF) undergoes premature senescence remains unclear. This study investigates the roles of senescent epithelial cells in OSF. METHODS: The immunohistoche...

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Detalles Bibliográficos
Autores principales:	Wang, Zijia, Han, Ying, Peng, Ying, Shao, Shuhui, Nie, Huanquan, Xia, Kun, Xiong, Haofeng, Su, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122456/ https://www.ncbi.nlm.nih.gov/pubmed/37096061 http://dx.doi.org/10.7717/peerj.15158

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