In Vitro Characterization of Motor Neurons and Purkinje Cells Differentiated from Induced Pluripotent Stem Cells Generated from Patients with Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disease mainly characterized by spasticity in the lower limbs and poor muscle control. The disease is caused by mutations in the SACS gene leading in most cases to a loss of function of the sacsin...

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Detalles Bibliográficos
Autores principales: Louit, Aurélie, Beaudet, Marie-Josée, Blais, Mathieu, Gros-Louis, François, Dupré, Nicolas, Berthod, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122584/
https://www.ncbi.nlm.nih.gov/pubmed/37096129
http://dx.doi.org/10.1155/2023/1496597

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