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TGF-β Activated Kinase 1 (TAK1) Is Activated in Microglia After Experimental Epilepsy and Contributes to Epileptogenesis

Increasing evidence suggests that inflammation promotes epileptogenesis. TAK1 is a central enzyme in the upstream pathway of NF-κB and is known to play a central role in promoting neuroinflammation in neurodegenerative diseases. Here, we investigated the cellular role of TAK1 in experimental epileps...

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Detalles Bibliográficos
Autores principales: Khan, Dilaware, Bedner, Peter, Müller, Julia, Lülsberg, Fabienne, Henning, Lukas, Prinz, Marco, Steinhäuser, Christian, Muhammad, Sajjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122619/
https://www.ncbi.nlm.nih.gov/pubmed/36862288
http://dx.doi.org/10.1007/s12035-023-03290-2