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Spontaneous tumor regression mediated by human T cells in a humanized immune system mouse model

Immunodeficient mice reconstituted with a human immune system (HIS mice) give rise to human T cells, which make them an attractive system to study human immune responses to tumors. However, such HIS mice typically exhibit sub-optimal responses to immune challenges as well as fail to develop antigen-...

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Detalles Bibliográficos
Autores principales: Patel, A. K., Dhanik, Ankur, Lim, Wei Keat, Adler, Christina, Ni, Min, Wei, Yi, Zhong, Maggie, Nguyen, Cindy, Zhong, Jun, Lu, Yi-Fen, Thurston, Gavin, Macdonald, Lynn, Murphy, Andrew, Gurer, Cagan, Frleta, Davor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122651/
https://www.ncbi.nlm.nih.gov/pubmed/37087494
http://dx.doi.org/10.1038/s42003-023-04824-z