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Potential utility of risk stratification for multicancer screening with liquid biopsy tests

Our proof-of-concept study reveals the potential of risk stratification by the combined effects of age, polygenic risk scores (PRS), and non-genetic risk factors in increasing the risk-benefit balance of rapidly emerging non-invasive multicancer early detection (MCED) liquid biopsy tests. We develop...

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Detalles Bibliográficos
Autores principales: Kim, Elle S., Scharpf, Robert B., Garcia-Closas, Montserrat, Visvanathan, Kala, Velculescu, Victor E., Chatterjee, Nilanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122653/
https://www.ncbi.nlm.nih.gov/pubmed/37087533
http://dx.doi.org/10.1038/s41698-023-00377-w

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