IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings

Transposases are ubiquitous enzymes that catalyze DNA rearrangement events with broad impacts on gene expression, genome evolution, and the spread of drug-resistance in bacteria. Here, we use biochemical and structural approaches to define the molecular determinants by which IstA, a transposase pres...

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Detalles Bibliográficos
Autores principales: Spínola-Amilibia, Mercedes, Araújo-Bazán, Lidia, de la Gándara, Álvaro, Berger, James M., Arias-Palomo, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122671/
https://www.ncbi.nlm.nih.gov/pubmed/37087515
http://dx.doi.org/10.1038/s41467-023-38071-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122671/
https://www.ncbi.nlm.nih.gov/pubmed/37087515
http://dx.doi.org/10.1038/s41467-023-38071-x

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