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IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings
Transposases are ubiquitous enzymes that catalyze DNA rearrangement events with broad impacts on gene expression, genome evolution, and the spread of drug-resistance in bacteria. Here, we use biochemical and structural approaches to define the molecular determinants by which IstA, a transposase pres...
Autores principales: | Spínola-Amilibia, Mercedes, Araújo-Bazán, Lidia, de la Gándara, Álvaro, Berger, James M., Arias-Palomo, Ernesto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122671/ https://www.ncbi.nlm.nih.gov/pubmed/37087515 http://dx.doi.org/10.1038/s41467-023-38071-x |
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