Cntnap4 partial deficiency exacerbates α-synuclein pathology through astrocyte–microglia C3-C3aR pathway

Parkinson’s disease (PD) is the most common progressive neurodegenerative movement disorder, which is characterized by dopaminergic (DA) neuron death and the aggregation of neurotoxic α-synuclein. Cntnap4, a risk gene of autism, has been implicated to participate in PD pathogenesis. Here we showed C...

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Detalles Bibliográficos
Autores principales: Zhang, Wenlong, Ding, Liuyan, Chen, Huaqing, Zhang, Mengran, Ma, Runfang, Zheng, Shaohui, Gong, Junwei, Zhang, Zhiling, Xu, Huaxi, Xu, Pingyi, Zhang, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122675/
https://www.ncbi.nlm.nih.gov/pubmed/37087484
http://dx.doi.org/10.1038/s41419-023-05807-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122675/
https://www.ncbi.nlm.nih.gov/pubmed/37087484
http://dx.doi.org/10.1038/s41419-023-05807-y

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