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Single Nucleotide Polymorphism rs9277336 Controls the Nuclear Alpha Actinin 4‐Human Leukocyte Antigen‐DPA1 Axis and Pulmonary Endothelial Pathophenotypes in Pulmonary Arterial Hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a complex, fatal disease where disease severity has been associated with the single nucleotide polymorphism (SNP) rs2856830, located near the human leukocyte antigen DPA1 (HLA‐DPA1) gene. We aimed to define the genetic architecture of functional v...

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Detalles Bibliográficos
Autores principales:	Hafeez, Neha, Kirillova, Anna, Yue, Yunshan, Rao, Rashmi J., Kelly, Neil J., El Khoury, Wadih, Al Aaraj, Yassmin, Tai, Yi‐Yin, Handen, Adam, Tang, Ying, Jiang, Danli, Wu, Ting, Zhang, Yingze, McNamara, Dennis, Kudryashova, Tatiana V., Goncharova, Elena A., Goncharov, Dmitry, Bertero, Thomas, Nouraie, Mehdi, Li, Gang, Sun, Wei, Chan, Stephen Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122886/ https://www.ncbi.nlm.nih.gov/pubmed/36974749 http://dx.doi.org/10.1161/JAHA.122.027894

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