Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic
Our case report highlights the importance of understanding various mechanisms of an atrioventricular block (AVB) and recognizing potential iatrogenic culprits. Despite the prevalent use of second-generation antipsychotics and the growing popularity of long-acting formulations, it is not routinely re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123026/ https://www.ncbi.nlm.nih.gov/pubmed/37101998 http://dx.doi.org/10.7759/cureus.36650 |
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author | Harrisingh, Kamahl Cu, Cameron Le, Marjolein Le Benhayon, Daniel |
author_facet | Harrisingh, Kamahl Cu, Cameron Le, Marjolein Le Benhayon, Daniel |
author_sort | Harrisingh, Kamahl |
collection | PubMed |
description | Our case report highlights the importance of understanding various mechanisms of an atrioventricular block (AVB) and recognizing potential iatrogenic culprits. Despite the prevalent use of second-generation antipsychotics and the growing popularity of long-acting formulations, it is not routinely recognized as a cause for AVB. Second-generation antipsychotics such as risperidone have a dose-dependent pro-arrhythmic effect and are known to cause first-degree AVB. Our case presents an opportunity to recognize an unappreciated cause for AVB and switch to safer alternatives. In the era of long-acting injectables, it is important to monitor for these effects prior to escalating doses and risking high-degree AVB. |
format | Online Article Text |
id | pubmed-10123026 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-101230262023-04-25 Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic Harrisingh, Kamahl Cu, Cameron Le, Marjolein Le Benhayon, Daniel Cureus Cardiology Our case report highlights the importance of understanding various mechanisms of an atrioventricular block (AVB) and recognizing potential iatrogenic culprits. Despite the prevalent use of second-generation antipsychotics and the growing popularity of long-acting formulations, it is not routinely recognized as a cause for AVB. Second-generation antipsychotics such as risperidone have a dose-dependent pro-arrhythmic effect and are known to cause first-degree AVB. Our case presents an opportunity to recognize an unappreciated cause for AVB and switch to safer alternatives. In the era of long-acting injectables, it is important to monitor for these effects prior to escalating doses and risking high-degree AVB. Cureus 2023-03-24 /pmc/articles/PMC10123026/ /pubmed/37101998 http://dx.doi.org/10.7759/cureus.36650 Text en Copyright © 2023, Harrisingh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Harrisingh, Kamahl Cu, Cameron Le, Marjolein Le Benhayon, Daniel Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic |
title | Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic |
title_full | Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic |
title_fullStr | Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic |
title_full_unstemmed | Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic |
title_short | Teetering on the Edge: Second-Degree Atrioventricular Block Following Long-Acting Second-Generation Antipsychotic |
title_sort | teetering on the edge: second-degree atrioventricular block following long-acting second-generation antipsychotic |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123026/ https://www.ncbi.nlm.nih.gov/pubmed/37101998 http://dx.doi.org/10.7759/cureus.36650 |
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