Cargando…

Weak tension accelerates hybridization and dehybridization of short oligonucleotides

The hybridization and dehybridization of DNA subject to tension is relevant to fundamental genetic processes and to the design of DNA-based mechanobiology assays. While strong tension accelerates DNA melting and decelerates DNA annealing, the effects of tension weaker than 5 pN are less clear. In th...

Descripción completa

Detalles Bibliográficos
Autores principales: Hart, Derek J, Jeong, Jiyoun, Gumbart, James C, Kim, Harold D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123125/
https://www.ncbi.nlm.nih.gov/pubmed/36869666
http://dx.doi.org/10.1093/nar/gkad118