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Weak tension accelerates hybridization and dehybridization of short oligonucleotides
The hybridization and dehybridization of DNA subject to tension is relevant to fundamental genetic processes and to the design of DNA-based mechanobiology assays. While strong tension accelerates DNA melting and decelerates DNA annealing, the effects of tension weaker than 5 pN are less clear. In th...
Autores principales: | Hart, Derek J, Jeong, Jiyoun, Gumbart, James C, Kim, Harold D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123125/ https://www.ncbi.nlm.nih.gov/pubmed/36869666 http://dx.doi.org/10.1093/nar/gkad118 |
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