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Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived cultures

The brain is arguably the most complex part of the human body in form and function. Much remains unclear about the molecular mechanisms that regulate its normal and pathological physiology. This lack of knowledge largely stems from the inaccessible nature of the human brain, and the limitation of an...

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Detalles Bibliográficos
Autores principales: Ahmed, Mai, Muffat, Julien, Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123288/
https://www.ncbi.nlm.nih.gov/pubmed/37101616
http://dx.doi.org/10.3389/fcell.2023.1158373