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Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study

PURPOSE: To compare the efficacy of two surgical techniques used to remove silicone oil (SiO) emulsion tamponade after pars plana vitrectomy: triple air–fluid exchange (AFX) and balanced salt solution lavage (BSSL). METHODS: X-ray photoemission spectroscopy measured silicon content of the dry residu...

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Autores principales: Rossi, Tommaso, Canepa, Paolo, Cavalleri, Ornella, Rolandi, Ranieri, Querzoli, Giorgio, D'Agostino, Isabella, Telani, Serena, Ripandelli, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123323/
https://www.ncbi.nlm.nih.gov/pubmed/37070937
http://dx.doi.org/10.1167/tvst.12.4.21
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author Rossi, Tommaso
Canepa, Paolo
Cavalleri, Ornella
Rolandi, Ranieri
Querzoli, Giorgio
D'Agostino, Isabella
Telani, Serena
Ripandelli, Guido
author_facet Rossi, Tommaso
Canepa, Paolo
Cavalleri, Ornella
Rolandi, Ranieri
Querzoli, Giorgio
D'Agostino, Isabella
Telani, Serena
Ripandelli, Guido
author_sort Rossi, Tommaso
collection PubMed
description PURPOSE: To compare the efficacy of two surgical techniques used to remove silicone oil (SiO) emulsion tamponade after pars plana vitrectomy: triple air–fluid exchange (AFX) and balanced salt solution lavage (BSSL). METHODS: X-ray photoemission spectroscopy measured silicon content of the dry residue of fluid samples taken during AFX and BSSL. Ten patients underwent AFX and five BSSL. Three fluid samples were taken per patient, and the dry residue of 10 drops per sample were analyzed. A fluid sample from a patient who never received SiO tamponade was also analyzed to set a “blank” reference sample. RESULTS: Patients’ demographics showed no significant difference. Sample 1 of the two groups contained comparable silicon content while samples 2 and 3 of the AFX group contained significantly more silicon than that of the BSSL group (15.0 ± 0.1 and 12.0 ± 0.9 for the AFX group vs. 10.7 ± 1.4 and 5.2 ± 0.6 for the BSSL group, respectively; P < 0.05). The cumulative amount of silicon in the three successive samples was also significantly higher for the AFX group (42.3 ± 1.6 vs. 32 ± 2; P < 0.0001). The average silicon content ratio of consecutive samples was significantly higher for the AFX group compared to the BSSL group (0.90 ± 0.01 vs. 0.58 ± 0.06; P = 0.006). CONCLUSIONS: Triple AFX removed more silicon than triple lavage. The eye wall actively interacts with silicon emulsion retaining silicon content rather than behaving as a neutral container. TRANSLATIONAL RELEVANCE: Triple air–fluid exchange removed more silicon than BSS lavage. Neither technique behaved as a well-mixed box dilution, suggesting the eye walls actively retain emulsion and a dynamic equilibrium is established between silicon dispersion and the eye wall surface.
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spelling pubmed-101233232023-04-25 Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study Rossi, Tommaso Canepa, Paolo Cavalleri, Ornella Rolandi, Ranieri Querzoli, Giorgio D'Agostino, Isabella Telani, Serena Ripandelli, Guido Transl Vis Sci Technol Retina PURPOSE: To compare the efficacy of two surgical techniques used to remove silicone oil (SiO) emulsion tamponade after pars plana vitrectomy: triple air–fluid exchange (AFX) and balanced salt solution lavage (BSSL). METHODS: X-ray photoemission spectroscopy measured silicon content of the dry residue of fluid samples taken during AFX and BSSL. Ten patients underwent AFX and five BSSL. Three fluid samples were taken per patient, and the dry residue of 10 drops per sample were analyzed. A fluid sample from a patient who never received SiO tamponade was also analyzed to set a “blank” reference sample. RESULTS: Patients’ demographics showed no significant difference. Sample 1 of the two groups contained comparable silicon content while samples 2 and 3 of the AFX group contained significantly more silicon than that of the BSSL group (15.0 ± 0.1 and 12.0 ± 0.9 for the AFX group vs. 10.7 ± 1.4 and 5.2 ± 0.6 for the BSSL group, respectively; P < 0.05). The cumulative amount of silicon in the three successive samples was also significantly higher for the AFX group (42.3 ± 1.6 vs. 32 ± 2; P < 0.0001). The average silicon content ratio of consecutive samples was significantly higher for the AFX group compared to the BSSL group (0.90 ± 0.01 vs. 0.58 ± 0.06; P = 0.006). CONCLUSIONS: Triple AFX removed more silicon than triple lavage. The eye wall actively interacts with silicon emulsion retaining silicon content rather than behaving as a neutral container. TRANSLATIONAL RELEVANCE: Triple air–fluid exchange removed more silicon than BSS lavage. Neither technique behaved as a well-mixed box dilution, suggesting the eye walls actively retain emulsion and a dynamic equilibrium is established between silicon dispersion and the eye wall surface. The Association for Research in Vision and Ophthalmology 2023-04-18 /pmc/articles/PMC10123323/ /pubmed/37070937 http://dx.doi.org/10.1167/tvst.12.4.21 Text en Copyright 2023 The Authors https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License.
spellingShingle Retina
Rossi, Tommaso
Canepa, Paolo
Cavalleri, Ornella
Rolandi, Ranieri
Querzoli, Giorgio
D'Agostino, Isabella
Telani, Serena
Ripandelli, Guido
Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study
title Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study
title_full Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study
title_fullStr Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study
title_full_unstemmed Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study
title_short Silicone Oil Tamponade Removal: Which Technique Is More Effective? An X-Ray Photoemission Spectroscopy Study
title_sort silicone oil tamponade removal: which technique is more effective? an x-ray photoemission spectroscopy study
topic Retina
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123323/
https://www.ncbi.nlm.nih.gov/pubmed/37070937
http://dx.doi.org/10.1167/tvst.12.4.21
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