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A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-b]quinoxaline derivatives hybrid with a sulfonamide moiety

A new series of 6-(pyrrolidin-1-ylsulfonyl)-[1,3]dithiolo[4,5-b]quinoxaline-2-ylidines 10a–f, 12, 14, 16, and 18 were designed, synthesized, and evaluated for their in vitro anticancer activity. The structures of the novel compounds were systematically characterized by (1)H NMR, (13)C NMR, and eleme...

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Detalles Bibliográficos
Autores principales: Ismail, Mostafa A., Abusaif, Moustafa S., El-Gaby, Mohamed S. A., Ammar, Yousry A., Ragab, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123497/
https://www.ncbi.nlm.nih.gov/pubmed/37101951
http://dx.doi.org/10.1039/d3ra01635h