Cargando…
A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-b]quinoxaline derivatives hybrid with a sulfonamide moiety
A new series of 6-(pyrrolidin-1-ylsulfonyl)-[1,3]dithiolo[4,5-b]quinoxaline-2-ylidines 10a–f, 12, 14, 16, and 18 were designed, synthesized, and evaluated for their in vitro anticancer activity. The structures of the novel compounds were systematically characterized by (1)H NMR, (13)C NMR, and eleme...
Autores principales: | Ismail, Mostafa A., Abusaif, Moustafa S., El-Gaby, Mohamed S. A., Ammar, Yousry A., Ragab, Ahmed |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123497/ https://www.ncbi.nlm.nih.gov/pubmed/37101951 http://dx.doi.org/10.1039/d3ra01635h |
Ejemplares similares
-
Novel quinoxaline-3-propanamides as VGFR-2 inhibitors and apoptosis inducers
por: Ismail, Magda M. F., et al.
Publicado: (2023) -
Antibiofilm and Anti-Quorum-Sensing Activities of Novel Pyrazole and Pyrazolo[1,5-a]pyrimidine Derivatives as Carbonic Anhydrase I and II Inhibitors: Design, Synthesis, Radiosterilization, and Molecular Docking Studies
por: Ragab, Ahmed, et al.
Publicado: (2023) -
Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: synthesis, biological evaluation and molecular docking
por: Ghorab, Mostafa M., et al.
Publicado: (2017) -
Anticancer Effects with Molecular Docking Confirmation of Newly Synthesized Isatin Sulfonamide Molecular Hybrid Derivatives against Hepatic Cancer Cell Lines
por: Eldeeb, Mahmoud, et al.
Publicado: (2022) -
The Antiproliferative and Apoptotic Effects of a Novel Quinazoline Carrying Substituted-Sulfonamides: In Vitro and Molecular Docking Study
por: Alqahtani, Ali S., et al.
Publicado: (2022)