Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2

Effective drugs with broad spectrum safety profile to all people are highly expected to combat COVID-19 caused by SARS-CoV-2. Here we report that nelfinavir, an FDA approved drug for the treatment of HIV infection, is effective against SARS-CoV-2 and COVID-19. Preincubation of nelfinavir could inhib...

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Detalles Bibliográficos
Autores principales: Xu, Zhijian, Shi, Danrong, Han, Jian-Bao, Ling, Yun, Jiang, Xiangrui, Lu, Xiangyun, Li, Chuan, Gong, Likun, Ge, Guangbo, Zhang, Yani, Zang, Yi, Song, Tian-Zhang, Feng, Xiao-Li, Tian, Ren-Rong, Ji, Jia, Zhu, Miaojin, Wu, Nanping, Wu, Chunhui, Wang, Zhen, Xu, Yechun, Peng, Cheng, Zheng, Min, Yang, Junling, Du, Feifei, Wu, Junliang, Wang, Peipei, Shen, Jingshan, Zhang, Jianliang, Zheng, Yong-Tang, Yao, Hangping, Zhu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123561/
https://www.ncbi.nlm.nih.gov/pubmed/37095086
http://dx.doi.org/10.1038/s41392-023-01429-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123561/
https://www.ncbi.nlm.nih.gov/pubmed/37095086
http://dx.doi.org/10.1038/s41392-023-01429-0

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