Binding affinity improvement analysis of multiple-mutant Omicron on 2019-nCov to human ACE2 by in silico predictions

CONTEXT: Since the outbreak of COVID-19 in 2019, the 2019-nCov coronavirus has appeared diverse mutational characteristics due to its own flexible conformation. One multiple-mutant strain (Omicron) with surprisingly infective activity outburst, and affected the biological activities of current drugs...

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Detalles Bibliográficos
Autores principales: Li, Bo, Guo, Jindan, Hu, Wenxiang, Chen, Yubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123576/
https://www.ncbi.nlm.nih.gov/pubmed/37093365
http://dx.doi.org/10.1007/s00894-023-05536-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123576/
https://www.ncbi.nlm.nih.gov/pubmed/37093365
http://dx.doi.org/10.1007/s00894-023-05536-1

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