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Post-Polio Syndrome Revisited

Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. PPS afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (MNDs), such a...

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Detalles Bibliográficos
Autores principales: Punsoni, Michael, Lakis, Nelli S., Mellion, Michelle, de la Monte, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123742/
https://www.ncbi.nlm.nih.gov/pubmed/37092507
http://dx.doi.org/10.3390/neurolint15020035
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author Punsoni, Michael
Lakis, Nelli S.
Mellion, Michelle
de la Monte, Suzanne M.
author_facet Punsoni, Michael
Lakis, Nelli S.
Mellion, Michelle
de la Monte, Suzanne M.
author_sort Punsoni, Michael
collection PubMed
description Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. PPS afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. Herein, we report a case of PPS in a 68-year-old man with a remote history of bulbar and cervical cord involvement by poliomyelitis, review the relevant literature, and contrast the salient histopathologic features that distinguish our case of PPS from ALS.
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spelling pubmed-101237422023-04-25 Post-Polio Syndrome Revisited Punsoni, Michael Lakis, Nelli S. Mellion, Michelle de la Monte, Suzanne M. Neurol Int Case Report Post-polio syndrome (PPS) is characterized by recrudescence or worsening of motor neuron disease symptoms decades after recovery from acute paralytic poliovirus infection, i.e., poliomyelitis. PPS afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. Herein, we report a case of PPS in a 68-year-old man with a remote history of bulbar and cervical cord involvement by poliomyelitis, review the relevant literature, and contrast the salient histopathologic features that distinguish our case of PPS from ALS. MDPI 2023-04-13 /pmc/articles/PMC10123742/ /pubmed/37092507 http://dx.doi.org/10.3390/neurolint15020035 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Punsoni, Michael
Lakis, Nelli S.
Mellion, Michelle
de la Monte, Suzanne M.
Post-Polio Syndrome Revisited
title Post-Polio Syndrome Revisited
title_full Post-Polio Syndrome Revisited
title_fullStr Post-Polio Syndrome Revisited
title_full_unstemmed Post-Polio Syndrome Revisited
title_short Post-Polio Syndrome Revisited
title_sort post-polio syndrome revisited
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123742/
https://www.ncbi.nlm.nih.gov/pubmed/37092507
http://dx.doi.org/10.3390/neurolint15020035
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