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Genetic inhibition of glutamate allosteric potentiation of GABA(A)Rs in mice results in hyperexcitability, leading to neurobehavioral abnormalities

The imbalance between neuronal excitation and inhibition (E/I) in neural circuit has been considered to be at the root of numerous brain disorders. We recently reported a novel feedback crosstalk between the excitatory neurotransmitter glutamate and inhibitory γ‐aminobutyric acid type A receptor (GA...

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Detalles Bibliográficos
Autores principales: Du, Yehong, Li, Junjie, Wang, Maoju, Tian, Qiuyun, Pang, Yayan, Wen, Ya, Wu, Dongchuan, Wang, Yu Tian, Dong, Zhifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123808/
https://www.ncbi.nlm.nih.gov/pubmed/37101797
http://dx.doi.org/10.1002/mco2.235

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