Associations between polygenic risk of substance use and use disorder and alcohol, cannabis, and nicotine use in adolescence and young adulthood in a longitudinal twin study

BACKGROUND: Recent well-powered genome-wide association studies have enhanced prediction of substance use outcomes via polygenic scores (PGSs). Here, we test (1) whether these scores contribute to prediction over-and-above family history, (2) the extent to which PGS prediction reflects inherited gen...

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Detalles Bibliográficos
Autores principales: Schaefer, Jonathan D., Jang, Seon-Kyeong, Clark, D. Angus, Deak, Joseph D., Hicks, Brian M., Iacono, William G., Liu, Mengzhen, McGue, Matt, Vrieze, Scott I., Wilson, Sylia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123833/
https://www.ncbi.nlm.nih.gov/pubmed/37310313
http://dx.doi.org/10.1017/S0033291721004116

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