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The activation of mTOR signalling modulates DNA methylation by enhancing DNMT1 translation in hepatocellular carcinoma

BACKGROUND: Both dysregulation of mechanistic target of rapamycin (mTOR) signalling and DNA methylation patterns have been shown to be closely associated with tumor progression and serve as promising targets for hepatocellular carcinoma (HCC) therapy. Although their respective roles in HCC have been...

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Detalles Bibliográficos
Autores principales: Chen, Mengke, Fang, Yi, Liang, Meinong, Zhang, Ning, Zhang, Xinyue, Xu, Lixia, Ren, Xuxin, Zhang, Qingfeng, Zhou, Yufeng, Peng, Sui, Yu, Jun, Zeng, Judeng, Li, Xiaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124003/
https://www.ncbi.nlm.nih.gov/pubmed/37088830
http://dx.doi.org/10.1186/s12967-023-04103-9