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Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology

BACKGROUND: Icariin (ICA), an active ingredient extracted from Epimedium species, has shown promising results in the treatment of Alzheimer's disease (AD), although its potential therapeutic mechanism remains largely unknown. This study aimed to investigate the therapeutic effects and the under...

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Detalles Bibliográficos
Autores principales: Liu, Yuqing, Li, Hongli, Wang, Xiaowei, Huang, Jianhua, Zhao, Di, Tan, Yejun, Zhang, Zheyu, Zhang, Zhen, Zhu, Lemei, Wu, Beibei, Chen, Zhibao, Peng, Weijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124026/
https://www.ncbi.nlm.nih.gov/pubmed/37095548
http://dx.doi.org/10.1186/s12967-023-04137-z