Toosendanin targeting eEF2 impedes Topoisomerase I & II protein translation to suppress esophageal squamous cell carcinoma growth

BACKGROUND: Although molecular targets such as HER2, TP53 and PIK3CA have been widely studied in esophageal cancer, few of them were successfully applied for clinical treatment. Therefore, it is urgent to discover novel actionable targets and inhibitors. Eukaryotic translational elongation factor 2...

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Detalles Bibliográficos
Autores principales: Jia, Xuechao, Wang, Penglei, Huang, Chuntian, Zhao, Dengyun, wu, Qiong, Lu, Bingbing, Nie, Wenna, Huang, Limeng, Tian, Xueli, li, Pan, Laster, Kyle Vaughn, Jiang, Yanan, Li, Xiang, Li, Honglin, Dong, Zigang, Liu, Kangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124032/
https://www.ncbi.nlm.nih.gov/pubmed/37088855
http://dx.doi.org/10.1186/s13046-023-02666-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124032/
https://www.ncbi.nlm.nih.gov/pubmed/37088855
http://dx.doi.org/10.1186/s13046-023-02666-5

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