Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development

The recent SARS-CoV-2 and mpox outbreaks have highlighted the need to expand our arsenal of broad-spectrum antiviral agents for future pandemic preparedness. Host-directed antivirals are an important tool to accomplish this as they typically offer protection against a broader range of viruses than d...

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Detalles Bibliográficos
Autores principales: Boulton, Stephen, Crupi, Mathieu J.F., Singh, Siddharth, Carter-Timofte, Madalina E., Azad, Taha, Organ, Bailey C., He, Xiaohong, Gill, Rida, Neault, Serge, Jamieson, Taylor, Dave, Jaahnavi, Kurmasheva, Naziia, Austin, Bradley, Petryk, Julia, Singaravelu, Ragunath, Huang, Ben Zhen, Franco, Noah, Babu, Kaaviya, Parks, Robin J., Ilkow, Carolina S., Olagnier, David, Bell, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124099/
https://www.ncbi.nlm.nih.gov/pubmed/37100284
http://dx.doi.org/10.1016/j.jbc.2023.104749

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