Automated biomarker candidate discovery in imaging mass spectrometry data through spatially localized Shapley additive explanations

The search for molecular species that are differentially expressed between biological states is an important step towards discovering promising biomarker candidates. In imaging mass spectrometry (IMS), performing this search manually is often impractical due to the large size and high-dimensionality...

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Detalles Bibliográficos
Autores principales: Tideman, Leonoor E.M., Migas, Lukasz G., Djambazova, Katerina V., Patterson, Nathan Heath, Caprioli, Richard M., Spraggins, Jeffrey M., Van de Plas, Raf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124144/
https://www.ncbi.nlm.nih.gov/pubmed/34482894
http://dx.doi.org/10.1016/j.aca.2021.338522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124144/
https://www.ncbi.nlm.nih.gov/pubmed/34482894
http://dx.doi.org/10.1016/j.aca.2021.338522

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