Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy

BACKGROUND: The wider application of T cells targeting viral tumor-antigens via their native receptors is hampered by the failure to expand potent tumor-specific T cells from patients. Here, we examine reasons for and solutions to this failure, taking as our model the preparation of Epstein-Barr vir...

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Detalles Bibliográficos
Autores principales: Sharma, Sandhya, Woods, Mae, Mehta, Naren U, Sauer, Tim, Parikh, Kathan S, Schmueck-Henneresse, Michael, Zhang, Huimin, Mehta, Birju, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124261/
https://www.ncbi.nlm.nih.gov/pubmed/37072346
http://dx.doi.org/10.1136/jitc-2022-006267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124261/
https://www.ncbi.nlm.nih.gov/pubmed/37072346
http://dx.doi.org/10.1136/jitc-2022-006267

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