Whole-genome and Epigenomic Landscapes of Malignant Gastrointestinal Stromal Tumors Harboring KIT Exon 11 557–558 Deletion Mutations

Gastrointestinal stromal tumors (GIST) with KIT exon 11 deletions involving in codons 557–558 (KIT Δ557–558) exhibit higher proliferation rates and shorter disease-free survival times compared with GISTs with other KIT exon 11 mutations. We analyzed 30 GIST cases and observed genomic instability and...

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Detalles Bibliográficos
Autores principales: Ohshima, Keiichi, Nagashima, Takeshi, Fujiya, Keiichi, Hatakeyama, Keiichi, Watanabe, Yuko, Morimoto, Kimiko, Kamada, Fukumi, Shimoda, Yuji, Ohnami, Sumiko, Naruoka, Akane, Serizawa, Masakuni, Ohnami, Shumpei, Kenmotsu, Hirotsugu, Shiomi, Akio, Tsubosa, Yasuhiro, Bando, Etsuro, Sugiura, Teiichi, Sugino, Takashi, Terashima, Masanori, Uesaka, Katsuhiko, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124575/
https://www.ncbi.nlm.nih.gov/pubmed/37377752
http://dx.doi.org/10.1158/2767-9764.CRC-22-0364

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