Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions

Retrospective investigation of archived tissue samples from 3 lions displaying nonsuppurative meningoencephalitis and vasculitis led to the detection of rustrela virus (RusV). We confirmed RusV antigen and RNA in cortical neurons, axons, astrocytes and Purkinje cells by reverse transcription quantit...

Descripción completa

Detalles Bibliográficos
Autores principales: de le Roi, Madeleine, Puff, Christina, Wohlsein, Peter, Pfaff, Florian, Beer, Martin, Baumgärtner, Wolfgang, Rubbenstroth, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124629/
https://www.ncbi.nlm.nih.gov/pubmed/37081716
http://dx.doi.org/10.3201/eid2905.230172
_version_ 1785029876106919936
author de le Roi, Madeleine
Puff, Christina
Wohlsein, Peter
Pfaff, Florian
Beer, Martin
Baumgärtner, Wolfgang
Rubbenstroth, Dennis
author_facet de le Roi, Madeleine
Puff, Christina
Wohlsein, Peter
Pfaff, Florian
Beer, Martin
Baumgärtner, Wolfgang
Rubbenstroth, Dennis
author_sort de le Roi, Madeleine
collection PubMed
description Retrospective investigation of archived tissue samples from 3 lions displaying nonsuppurative meningoencephalitis and vasculitis led to the detection of rustrela virus (RusV). We confirmed RusV antigen and RNA in cortical neurons, axons, astrocytes and Purkinje cells by reverse transcription quantitative PCR, immunohistochemistry, and in situ hybridization.
format Online
Article
Text
id pubmed-10124629
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-101246292023-05-01 Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions de le Roi, Madeleine Puff, Christina Wohlsein, Peter Pfaff, Florian Beer, Martin Baumgärtner, Wolfgang Rubbenstroth, Dennis Emerg Infect Dis Dispatch Retrospective investigation of archived tissue samples from 3 lions displaying nonsuppurative meningoencephalitis and vasculitis led to the detection of rustrela virus (RusV). We confirmed RusV antigen and RNA in cortical neurons, axons, astrocytes and Purkinje cells by reverse transcription quantitative PCR, immunohistochemistry, and in situ hybridization. Centers for Disease Control and Prevention 2023-05 /pmc/articles/PMC10124629/ /pubmed/37081716 http://dx.doi.org/10.3201/eid2905.230172 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
de le Roi, Madeleine
Puff, Christina
Wohlsein, Peter
Pfaff, Florian
Beer, Martin
Baumgärtner, Wolfgang
Rubbenstroth, Dennis
Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions
title Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions
title_full Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions
title_fullStr Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions
title_full_unstemmed Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions
title_short Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions
title_sort rustrela virus as putative cause of nonsuppurative meningoencephalitis in lions
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124629/
https://www.ncbi.nlm.nih.gov/pubmed/37081716
http://dx.doi.org/10.3201/eid2905.230172
work_keys_str_mv AT deleroimadeleine rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions
AT puffchristina rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions
AT wohlseinpeter rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions
AT pfaffflorian rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions
AT beermartin rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions
AT baumgartnerwolfgang rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions
AT rubbenstrothdennis rustrelavirusasputativecauseofnonsuppurativemeningoencephalitisinlions

Ejemplares similares