Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis–related strains as parents. Our findings highlight the existence of poorly sampled Leishma...

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Detalles Bibliográficos
Autores principales: Van den Broeck, Frederik, Heeren, Senne, Maes, Ilse, Sanders, Mandy, Cotton, James A., Cupolillo, Elisa, Alvarez, Eugenia, Garcia, Lineth, Tasia, Maureen, Marneffe, Alice, Dujardin, Jean-Claude, Van der Auwera, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124652/
https://www.ncbi.nlm.nih.gov/pubmed/37081624
http://dx.doi.org/10.3201/eid2905.221456
Descripción
Sumario:We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis–related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

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