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Measurement of Complement Activation via Plasma-Soluble C5b-9 Comparison with Terminal Complement Complex Staining in a Series of Kidney Biopsies

INTRODUCTION: With the emergence of therapeutic complement inhibitors, there is a need to identify patients with complement-driven inflammation. C5b-9 is the terminal product of the three complement pathways and therefore a marker of total complement activation. We present a pilot study which aims t...

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Detalles Bibliográficos
Autores principales: Wijaya, Carolyn, Burns, Christine, Hall, Sharron, Farmer, Melissa, Jones, Denise, Rowlandson, Matthew, Choi, Peter, Formby, Mark, de Malmanche, Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124756/
https://www.ncbi.nlm.nih.gov/pubmed/36917968
http://dx.doi.org/10.1159/000529734