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Omicron Spike Protein is Vulnerable to Reduction

SARS-CoV-2 virus spike (S) protein is an envelope protein responsible for binding to the ACE2 receptor, driving subsequent entry into host cells. The existence of multiple disulfide bonds in the S protein makes it potentially susceptible to reductive cleavage. Using a tri-part split luciferase-based...

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Detalles Bibliográficos
Autores principales:	Yao, Zhong, Geng, Betty, Marcon, Edyta, Pu, Shuye, Tang, Hua, Merluza, John, Bello, Alexander, Snider, Jamie, Lu, Ping, Wood, Heidi, Stagljar, Igor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Ltd. 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125213/ https://www.ncbi.nlm.nih.gov/pubmed/37100168 http://dx.doi.org/10.1016/j.jmb.2023.168128

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