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Assessing Tissue Fixation Time and Quality with Label-free Mid Infrared Spectroscopy and Machine Learning
OBJECTIVES: This work investigates whether changes in a biospecimen's molecular composition from formaldehyde fixation drive changes in the mid infrared (MID-IR) spectrum. Our ultimate goal was to develop an analytical metrology that could be used to accurately determine the fixation time of a...
Autores principales: | Bauer, Daniel R., Chafin, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125394/ https://www.ncbi.nlm.nih.gov/pubmed/36516138 http://dx.doi.org/10.1089/bio.2022.0108 |
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