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Assessing Tissue Fixation Time and Quality with Label-free Mid Infrared Spectroscopy and Machine Learning

OBJECTIVES: This work investigates whether changes in a biospecimen's molecular composition from formaldehyde fixation drive changes in the mid infrared (MID-IR) spectrum. Our ultimate goal was to develop an analytical metrology that could be used to accurately determine the fixation time of a...

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Detalles Bibliográficos
Autores principales: Bauer, Daniel R., Chafin, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125394/
https://www.ncbi.nlm.nih.gov/pubmed/36516138
http://dx.doi.org/10.1089/bio.2022.0108

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