Cargando…

5-Fluorouracil-Loaded PLGA Nanoparticles: Formulation, Physicochemical Characterisation, and In VitroAnti-Cancer Activity

The major goal of this investigation was to prepare a drug delivery of polymeric nanoparticles (NPs) from 5-fluorouracil (FU) that could be delivered intravenously and improve the therapeutic index of the FU. In order to achieve this, interfacial deposition method was used to prepare FU entrapped po...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gahtani, Reem M., Alqahtani, Ali, Alqahtani, Taha, Asiri, Saeed Ahmed, Mohamed, Jamal Moideen Muthu, Venkatesa Prabhu, S., Muluneh, Endalew Yaze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125733/ https://www.ncbi.nlm.nih.gov/pubmed/37102134 http://dx.doi.org/10.1155/2023/2334675

Ejemplares similares

Design, Physical Characterizations, and Biocompatibility of Cationic Solid Lipid Nanoparticles in HCT-116 and 16-HBE Cells: A Preliminary Study
por: Alamri, Ali, et al.
Publicado: (2023)

Human Hair Keratin Composite Scaffold: Characterisation and Biocompatibility Study on NIH 3T3 Fibroblast Cells
por: Mohamed, Jamal Moideen Muthu, et al.
Publicado: (2021)

Green spectrofluorimetric quantification of aspirin, olmesartan, and metoprolol in spiked human plasma
por: Alqahtani, Ali, et al.
Publicado: (2023)

Molecular Docking and Green Synthesis of Bioinorganic TiO(2) Nanoparticles against E.coli and S.aureus
por: Al-Serwi, Rasha Hamed, et al.
Publicado: (2022)

The Unique Carboxymethyl Fenugreek Gum Gel Loaded Itraconazole Self-Emulsifying Nanovesicles for Topical Onychomycosis Treatment
por: Alqahtani, Ali, et al.
Publicado: (2022)

Stoichiometrically Governed Curcumin Solid Dispersion and Its Cytotoxic Evaluation on Colorectal Adenocarcinoma Cells
por: Mohamed, Jamal Moideen Muthu, et al.
Publicado: (2020)

Preparation of Soluble Complex of Curcumin for the Potential Antagonistic Effects on Human Colorectal Adenocarcinoma Cells
por: Mohamed, Jamal Moideen Muthu, et al.
Publicado: (2021)

Superfast Synthesis of Stabilized Silver Nanoparticles Using Aqueous Allium sativum (Garlic) Extract and Isoniazid Hydrazide Conjugates: Molecular Docking and In-Vitro Characterizations
por: Mohamed, Jamal Moideen Muthu, et al.
Publicado: (2021)

Design, Preparation, and Physicochemical Characterisation of Alginate-Based Honey-Loaded Topical Formulations
por: Hossain, Md Lokman, et al.
Publicado: (2023)

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation
por: Alqahtani, Taha, et al.
Publicado: (2022)

Therapeutic Efficacy of a Formulation Prepared with Linum usitatissimum L., Plantago ovata Forssk., and Honey on Uncomplicated Pelvic Inflammatory Disease Analyzed with Machine Learning Techniques
por: Qayyum, Sana, et al.
Publicado: (2023)

Development of Sulfadiazine-Decorated PLGA Nanoparticles Loaded with 5-Fluorouracil and Cell Viability
por: Guimarães, Pedro Pires Goulart, et al.
Publicado: (2015)

Physical PEGylation Enhances The Cytotoxicity Of 5-Fluorouracil-Loaded PLGA And PCL Nanoparticles
por: Ashour, Abdelkader E, et al.
Publicado: (2019)

Effect of Dexamethasone-Loaded PLGA Nanoparticles on Oral Mucositis Induced by 5-Fluorouracil
por: Ribeiro, Susana Barbosa, et al.
Publicado: (2021)

Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals
por: Sultan, Muhammad H., et al.
Publicado: (2023)

Formulation and Evaluation of Diclofenac Potassium Gel in Sports Injuries with and without Phonophoresis
por: Bukhari, Komal Ammar, et al.
Publicado: (2022)

Biological evaluation of 5-fluorouracil nanoparticles for cancer chemotherapy and its dependence on the carrier, PLGA
por: Nair K, Lekha, et al.
Publicado: (2011)

An Ideal Approach for Enhancing 5-Fluorouracil Anticancer Efficacy by Nanoemulsion for Cytotoxicity against a Human Hepatoma Cell Line (HepG2 Cells)
por: Mohamed, Jamal Moideen Muthu, et al.
Publicado: (2022)

Insights into the Effect of Chitosan and β-Cyclodextrin Hybridization of Zeolite-A on Its Physicochemical and Cytotoxic Properties as a Bio-Carrier for 5-Fluorouracil: Equilibrium and Release Kinetics Studies
por: Alqahtani, Mashael D., et al.
Publicado: (2023)

Recent advances in the formulation of PLGA microparticles for controlled drug delivery
por: Lagreca, Elena, et al.
Publicado: (2020)

Strong Selectional Forces Fine-Tune CpG Content in Genes Involved in Neurological Disorders as Revealed by Codon Usage Patterns
por: Khandia, Rekha, et al.
Publicado: (2022)

MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization
por: Alanazi, Jouri S., et al.
Publicado: (2022)

Formulation of Antimicrobial Tobramycin Loaded PLGA Nanoparticles via Complexation with AOT
por: Hill, Marcus, et al.
Publicado: (2019)

Formulation and Characterization of Ciprofloxacin loaded PLGA Microspheres for Applications in Orthopedic Infections
por: MOCANU, ANDREEA-GABRIELA, et al.
Publicado: (2017)

Formulation of PLGA nanoparticles containing short cationic peptide nucleic acids
por: Malik, Shipra, et al.
Publicado: (2020)

PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: effects of formulation parameters
por: Hernández-Giottonini, Karol Yesenia, et al.
Publicado: (2020)

PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies
por: Liu, Ying, et al.
Publicado: (2017)

Design, Formulation and Physicochemical Evaluation of Clotrimazole Chewing GumDesign, Formulation and Physicochemical Evaluation of Clotrimazole Chewing Gum
por: Aslani, Abolfazl, et al.
Publicado: (2021)

Antioxidant and Gastroprotective Activity of Suaeda fruticosa Forssk. Ex J.F.Gmel
por: Ayaz, Afsheen, et al.
Publicado: (2022)

Development of Rifapentine-Loaded PLGA-Based Nanoparticles: In vitro Characterisation and in vivo Study in Mice
por: Liang, Qiuzhen, et al.
Publicado: (2020)

Microfluidic-Assisted Preparation of 5-Fluorouracil-Loaded PLGA Nanoparticles as a Potential System for Colorectal Cancer Therapy
por: Ghasemi Toudeshkchouei, Mahtab, et al.
Publicado: (2020)

Enhanced antitumor efficacy in colon cancer using EGF functionalized PLGA nanoparticles loaded with 5-Fluorouracil and perfluorocarbon
por: Wu, Pingping, et al.
Publicado: (2020)

Application of the Box–Behnken design for the production of soluble curcumin: Skimmed milk powder inclusion complex for improving the treatment of colorectal cancer
por: Jamal Moideen, Muthu Mohamed, et al.
Publicado: (2020)

Formulation and Characterization of Antigen-loaded PLGA Nanoparticles for Efficient Cross-priming of the Antigen
por: Lee, Young-Ran, et al.
Publicado: (2011)

PLGA Biodegradable Nanoparticles Containing Perphenazine or Chlorpromazine Hydrochloride: Effect of Formulation and Release
por: Halayqa, Mohammed, et al.
Publicado: (2014)

Formulation and In vitro Interaction of Rhodamine-B Loaded PLGA Nanoparticles with Cardiac Myocytes
por: Jonderian, Antranik, et al.
Publicado: (2016)

Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy
por: Mietzner, Raphael, et al.
Publicado: (2020)

Formulation and evaluation of butenafine loaded PLGA-nanoparticulate laden chitosan nano gel
por: Alshehri, Sultan, et al.
Publicado: (2021)

Formulation, Characterization and Cytotoxicity Effects of Novel Thymoquinone-PLGA-PF68 Nanoparticles
por: Noor, Nurul Shahfiza, et al.
Publicado: (2021)

Design, Development, Physicochemical Characterization, and In Vitro Drug Release of Formoterol PEGylated PLGA Polymeric Nanoparticles
por: Vallorz, Ernest L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p1fs8rr59k3c01go3shhg1nbrp