Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia

Anti-melanoma differentiation-associated gene 5 (MDA-5) antibody-positive dermatomyositis is a disease with a poor prognosis associated with rapid progressive interstitial pneumonia. Autoimmune diseases have occasionally been reported to occur after hematopoietic stem cell transplantation (HSCT). We...

Descripción completa

Detalles Bibliográficos
Autores principales: Futamura, Mariko, Ozaki, Yoshio, Makino, Hidehiko, Tsujimoto, Saki, Shigesaka, Minoru, Tanaka, Akihiro, Shimamoto, Keiko, Son, Yonsu, Ito, Tomoki, Nomura, Shosaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125815/
https://www.ncbi.nlm.nih.gov/pubmed/36070956
http://dx.doi.org/10.2169/internalmedicine.9529-22
_version_ 1785030105515425792
author Futamura, Mariko
Ozaki, Yoshio
Makino, Hidehiko
Tsujimoto, Saki
Shigesaka, Minoru
Tanaka, Akihiro
Shimamoto, Keiko
Son, Yonsu
Ito, Tomoki
Nomura, Shosaku
author_facet Futamura, Mariko
Ozaki, Yoshio
Makino, Hidehiko
Tsujimoto, Saki
Shigesaka, Minoru
Tanaka, Akihiro
Shimamoto, Keiko
Son, Yonsu
Ito, Tomoki
Nomura, Shosaku
author_sort Futamura, Mariko
collection PubMed
description Anti-melanoma differentiation-associated gene 5 (MDA-5) antibody-positive dermatomyositis is a disease with a poor prognosis associated with rapid progressive interstitial pneumonia. Autoimmune diseases have occasionally been reported to occur after hematopoietic stem cell transplantation (HSCT). We experienced a case of anti-MDA-5 antibody-positive dermatomyositis after HSCT. In this case, a sufficient dose of cyclophosphamide could not be administered due to an impaired bone marrow function. We discuss the complications of autoimmune diseases after HSCT.
format Online
Article
Text
id pubmed-10125815
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-101258152023-04-26 Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia Futamura, Mariko Ozaki, Yoshio Makino, Hidehiko Tsujimoto, Saki Shigesaka, Minoru Tanaka, Akihiro Shimamoto, Keiko Son, Yonsu Ito, Tomoki Nomura, Shosaku Intern Med Case Report Anti-melanoma differentiation-associated gene 5 (MDA-5) antibody-positive dermatomyositis is a disease with a poor prognosis associated with rapid progressive interstitial pneumonia. Autoimmune diseases have occasionally been reported to occur after hematopoietic stem cell transplantation (HSCT). We experienced a case of anti-MDA-5 antibody-positive dermatomyositis after HSCT. In this case, a sufficient dose of cyclophosphamide could not be administered due to an impaired bone marrow function. We discuss the complications of autoimmune diseases after HSCT. The Japanese Society of Internal Medicine 2022-09-06 2023-04-01 /pmc/articles/PMC10125815/ /pubmed/36070956 http://dx.doi.org/10.2169/internalmedicine.9529-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Futamura, Mariko
Ozaki, Yoshio
Makino, Hidehiko
Tsujimoto, Saki
Shigesaka, Minoru
Tanaka, Akihiro
Shimamoto, Keiko
Son, Yonsu
Ito, Tomoki
Nomura, Shosaku
Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia
title Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia
title_full Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia
title_fullStr Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia
title_full_unstemmed Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia
title_short Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia
title_sort anti-mda-5 antibody-positive dermatomyositis after allogeneic bone marrow transplantation for acute transformation of chronic myelogenous leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125815/
https://www.ncbi.nlm.nih.gov/pubmed/36070956
http://dx.doi.org/10.2169/internalmedicine.9529-22
work_keys_str_mv AT futamuramariko antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT ozakiyoshio antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT makinohidehiko antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT tsujimotosaki antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT shigesakaminoru antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT tanakaakihiro antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT shimamotokeiko antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT sonyonsu antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT itotomoki antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia
AT nomurashosaku antimda5antibodypositivedermatomyositisafterallogeneicbonemarrowtransplantationforacutetransformationofchronicmyelogenousleukemia

Ejemplares similares