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An Analysis of COVID-19 Mortality During the Dominancy of Alpha, Delta, and Omicron in the USA
BACKGROUND: The objective of the study was to measure the risk of death due to COVID-19 in relation to individuals’ characteristics, and severity of their disease during the dominant periods of Alpha, Delta, and Omicron variants have influenced mortality rates. METHODS: This study was conducted usin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125879/ https://www.ncbi.nlm.nih.gov/pubmed/37083205 http://dx.doi.org/10.1177/21501319231170164 |
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author | Tabatabai, Mohammad Juarez, Paul D. Matthews-Juarez, Patricia Wilus, Derek M. Ramesh, Aramandla Alcendor, Donald J. Tabatabai, Niki Singh, Karan P. |
author_facet | Tabatabai, Mohammad Juarez, Paul D. Matthews-Juarez, Patricia Wilus, Derek M. Ramesh, Aramandla Alcendor, Donald J. Tabatabai, Niki Singh, Karan P. |
author_sort | Tabatabai, Mohammad |
collection | PubMed |
description | BACKGROUND: The objective of the study was to measure the risk of death due to COVID-19 in relation to individuals’ characteristics, and severity of their disease during the dominant periods of Alpha, Delta, and Omicron variants have influenced mortality rates. METHODS: This study was conducted using COVID-19 Centers for Disease Control and Prevention (CDC) Case Surveillance Public Data Taskforce for 57 states, and United States territories between January 1, 2020 and March 20, 2022. Multivariable binary Hyperbolastic regression of type I was used to analyzes the data. RESULTS: Seniors and ICU-admitted patients had the highest risk of death. For each additional percent increase in fully vaccinated individuals, the odds of death deceased by 1%. The odds of death prior to vaccine availability, compared to post vaccine availability, was 1.27. When comparing the time periods each variant was dominant, the odds of death was 3.45-fold higher during Delta compared to Alpha. All predictor variables had P-values ≤.001. CONCLUSION: There was a noticeable difference in the odds of death among subcategories of age, race/ethnicity, sex, PMCs, hospitalization, ICU, vaccine availability, variant, and percent of fully vaccinated individuals. |
format | Online Article Text |
id | pubmed-10125879 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-101258792023-04-25 An Analysis of COVID-19 Mortality During the Dominancy of Alpha, Delta, and Omicron in the USA Tabatabai, Mohammad Juarez, Paul D. Matthews-Juarez, Patricia Wilus, Derek M. Ramesh, Aramandla Alcendor, Donald J. Tabatabai, Niki Singh, Karan P. J Prim Care Community Health Original Research BACKGROUND: The objective of the study was to measure the risk of death due to COVID-19 in relation to individuals’ characteristics, and severity of their disease during the dominant periods of Alpha, Delta, and Omicron variants have influenced mortality rates. METHODS: This study was conducted using COVID-19 Centers for Disease Control and Prevention (CDC) Case Surveillance Public Data Taskforce for 57 states, and United States territories between January 1, 2020 and March 20, 2022. Multivariable binary Hyperbolastic regression of type I was used to analyzes the data. RESULTS: Seniors and ICU-admitted patients had the highest risk of death. For each additional percent increase in fully vaccinated individuals, the odds of death deceased by 1%. The odds of death prior to vaccine availability, compared to post vaccine availability, was 1.27. When comparing the time periods each variant was dominant, the odds of death was 3.45-fold higher during Delta compared to Alpha. All predictor variables had P-values ≤.001. CONCLUSION: There was a noticeable difference in the odds of death among subcategories of age, race/ethnicity, sex, PMCs, hospitalization, ICU, vaccine availability, variant, and percent of fully vaccinated individuals. SAGE Publications 2023-04-21 /pmc/articles/PMC10125879/ /pubmed/37083205 http://dx.doi.org/10.1177/21501319231170164 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Tabatabai, Mohammad Juarez, Paul D. Matthews-Juarez, Patricia Wilus, Derek M. Ramesh, Aramandla Alcendor, Donald J. Tabatabai, Niki Singh, Karan P. An Analysis of COVID-19 Mortality During the Dominancy of Alpha, Delta, and Omicron in the USA |
title | An Analysis of COVID-19 Mortality During the Dominancy of Alpha,
Delta, and Omicron in the USA |
title_full | An Analysis of COVID-19 Mortality During the Dominancy of Alpha,
Delta, and Omicron in the USA |
title_fullStr | An Analysis of COVID-19 Mortality During the Dominancy of Alpha,
Delta, and Omicron in the USA |
title_full_unstemmed | An Analysis of COVID-19 Mortality During the Dominancy of Alpha,
Delta, and Omicron in the USA |
title_short | An Analysis of COVID-19 Mortality During the Dominancy of Alpha,
Delta, and Omicron in the USA |
title_sort | analysis of covid-19 mortality during the dominancy of alpha,
delta, and omicron in the usa |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125879/ https://www.ncbi.nlm.nih.gov/pubmed/37083205 http://dx.doi.org/10.1177/21501319231170164 |
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