A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from patients with type 1 VWD

Type 1 von Willebrand disease (VWD) is associated with a reduction in qualitatively normal von Willebrand factor (VWF). Current diagnostic guidelines only take into consideration the contribution of basal VWF levels, despite a lack of correlation with bleeding severity. Defects in stimulated VWF rel...

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Detalles Bibliográficos
Autores principales: Kloosterman, Robert, Zago-Schmitt, Matteo, Grabell, Julie, Thibeault, Lisa, De Lima, Patricia A., Bowman, Mackenzie, Tyryshkin, Kathrin, Hindmarch, Charles C. T., Renwick, Neil, James, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125911/
https://www.ncbi.nlm.nih.gov/pubmed/36121439
http://dx.doi.org/10.1182/bloodadvances.2022007884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125911/
https://www.ncbi.nlm.nih.gov/pubmed/36121439
http://dx.doi.org/10.1182/bloodadvances.2022007884

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